Alzheimer's & Cognition
From the Journals
Loneliness tied to increased risk for Parkinson’s disease
The association between loneliness and incident PD was not moderated by sex, age, or polygenetic risk score.
Commentary
Multivitamins and dementia: Untangling the COSMOS study web
When you get a positive result in your research, it’s always exciting. But when a slew of studies that came before you are negative, you aren’t...
News
Unique twin study sheds new light on TBI and risk of cognitive decline
“We know that TBI increases the risk of dementia in later life, but we haven’t known if TBI affects cognitive function, causes cognitive decline...
News
How does lecanemab work in Alzheimer’s?
“In our study, we looked at lecanemab and found it can block the activation of the contact system, which could be one of the reasons that it works...
News
Sedentary lifestyle tied to increased dementia risk
Dementia risk was elevated whether participants were sedentary for 10 uninterrupted hours or multiple sedentary periods that totaled 10 hours over...
News
Abdominal fat linked to lower brain volume in midlife
“Overall, we found that both subcutaneous and visceral fat has similar levels of negative relationships with brain volumes.”
From the Journals
Dementia diagnosis a good time to reduce polypharmacy
Time of diagnosis can be a potential inflexion point for deprescribing long-term medications with safety risks, limited benefit, or possible...
Latest News
Most with early AD not eligible for new antiamyloid drugs
Older patients aren’t eligible largely because of the presence of medical conditions or neuroimaging findings.
From the Journals
Few meet eligibility for newer Alzheimer’s drugs
Fewer than 10% of early Alzheimer’s patients in a real-world cohort would qualify for trials of anti–amyloid-beta monoclonal antibodies, a study...
News
Which factors distinguish superagers from the rest of us?
The superagers indicated that generally they had been more active than the control subjects during their middle years.
From the Journals
‘Emerging’ biomarker may predict mild cognitive impairment years before symptoms
Low NPTX2 levels are predictive of MCI symptom onset more than 7 years in advance.