Pediatrics
News
Cost-effectiveness of CAR T-cell therapy
Tisagenlecleucel has the potential to be cost-effective for pediatric B-cell acute lymphoblastic leukemia (B-ALL) patients in the United States,...
News
Age limits restrict AYA participation in relevant trials
MUNICH—Age limits imposed in European countries can prevent adolescents and young adults (AYAs) from enrolling in appropriate clinical trials, a...
News
Study supports sequencing in kids with cancer
SAN DIEGO—Comprehensive next-generation sequencing is both feasible and clinically useful in pediatric cancer patients, a new study suggests....
From the Journals
Kymriah appears cost effective in analysis
The latest study on the CAR T therapy tisagenlecleucel for pediatric leukemia says it may be cost effective, provided that the long-term benefits...
News
Transfusion errors more common in kids than adults, study suggests
BOSTON—Even the most vigilant hospitals experience transfusion errors and problems with blood storage, according to researchers. A review of data...
News
Bacteremic sepsis in ALL tied to neurocognitive dysfunction
Bacteremic sepsis during acute lymphoblastic leukemia (ALL) treatment may contribute to neurocognitive dysfunction later in life, results of a...
News
Factors that may drive relapse in AYAs with ALL
New research suggests race, clinical trial participation, and treatment duration may influence the risk of relapse in adolescents and young adults...
News
Blinatumomab approved to treat ALL in Japan
The Japanese Ministry of Health, Labour and Welfare has approved blinatumomab (Blincyto®) for the treatment of relapsed or refractory B-cell acute...
News
Kids with BCP-ALL exhibit immunological disparities at birth
Patients who develop B-cell precursor acute lymphoblastic leukemia (BCP-ALL) in childhood may have dysregulated immune function at birth,...
News
Insights could change treatment, classification of MPAL
An extensive analysis of mixed phenotype acute leukemia (MPAL) has led to new insights that may have implications for disease classification and...
News
Prophylaxis reduces bacteremia in some kids
In a phase 3 study, levofloxacin prophylaxis significantly reduced bacteremia in children with acute leukemias who received intensive chemotherapy...