Non-Hodgkin Lymphoma
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How CLL evades the immune system
Photo courtesy of Monash University A study published in Leukemia has revealed a mechanism by which chronic lymphocytic leukemia (CLL) evades the...
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Mutations may contribute to CTCL
mycosis fungoides Researchers have identified 15 mutations that may drive cutaneous T-cell lymphoma (CTCL). The team sequenced normal and...
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Topical gel appears safe, effective in CTCL
treatment (top) and 16 weeks after treatment began Photo from Penn Medicine Results of a phase 1 trial suggest a topical gel can prompt...
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Drug gets orphan designation for CTCL
The European Commission has granted orphan drug designation to synthetic hypericin, the active pharmaceutical ingredient in SGX301, for the...
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Health Canada grants drug conditional approval for MCL
Photo courtesy of Janssen Biotech, Inc. Health Canada has granted conditional approval for the BTK inhibitor ibrutinib (Imbruvica) to treat...
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Tool identifies optimal TKI for cancers
Photo courtesy of the University of Colorado Researchers say they have developed a tool that allows us to determine which tyrosine kinase...
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Analysis reveals ‘distinctive biology’ of CTCL
New research suggests cutaneous T-cell lymphoma (CTCL) is driven by a plethora of genetic mutations. Investigators conducted a genomic analysis...
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DLBCL tied to metabolic disruption
Researchers say they have found evidence linking disrupted metabolism and diffuse large B-cell lymphoma (DLBCL). “The link between metabolism and...
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Response to ibrutinib varies by DLBCL subtype
Photo by Larry Young Responses to the BTK inhibitor ibrutinib differ according to a patient’s subtype of diffuse large B-cell lymphoma (DLBCL),...
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Ibrutinib approved to treat WM in EU
The European Commission has granted marketing authorization for ibrutinib (Imbruvica) to treat Waldenstrom’s macroglobulinemia (WM). The Bruton’s...
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How B-cell lymphoma evades NK cells
Image by Joshua Strokes Researchers say they have determined how lymphoma cells evade natural killer (NK) cells, and this discovery has revealed...