Myelodysplastic Syndrome
News
Understanding the role of del(7q) in MDS
Image by James Thomson A new study has improved researchers’ understanding of a genetic defect associated with myelodysplastic syndromes (MDS),...
Conference Coverage
Iron chelation improves survival in lower-risk MDS
Photo courtesy of ASH SAN FRANCISCO—Iron chelation therapy significantly improves survival for patients with lower-risk myelodysplastic syndrome...
Conference Coverage
Two activin receptor fusion proteins show promise in anemia
site of the ASH Annual Meeting Photo courtesy of ASH SAN FRANCISCO—Two activin receptor fusion proteins, luspatercept and sotatercept, increased...
Conference Coverage
Investigational sotatercept improves heme parameters in MDS
Key clinical point: Sotatercept is a first-in-its-class agent that stimulates erythropoiesis through a mechanism different from that of...
News
Vitiligo, alopecia more likely in GVHD when donor is female and recipient is male
Key clinical point: Female-to-male stem cell donation ups the risk for vitiligo in GVHD. Major finding: 14 of the 15 patients who developed...
News
FDA approves generic decitabine for MDS
Credit: Bill Branson The US Food and Drug Administration (FDA) has approved decitabine for injection, a generic version of Dacogen, to treat...
News
Drugs can increase risk of MDS and AML
A class of immunosuppressive agents appear to increase the risk of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) in patients...
Conference Coverage
AG-221 sparked durable responses in hematologic cancers
Key clinical point: AG-221 could shift the treatment for IDH2 mutation-positive hematologic cancers. Major finding: Fourteen of 25 patients...
Conference Coverage
Inhibitor shows promise for hematologic disorders
Photo courtesy of EHA MILAN—The IDH2 inhibitor AG-221 is well-tolerated and exhibits durable clinical activity in patients with hematologic...
News
Group finds cancer stem cells in MDS patients
Credit: NIH A new study provides “conclusive evidence” to support the existence of cancer stem cells in patients with myelodysplastic syndromes (...
News
Testing reveals abnormalities in CN-AML/MDS
Credit: NIGMS NASHVILLE—New research suggests we may need to use more sensitive methods to analyze patients with cytogenetically normal acute...