Leukemia, Myelodysplasia, Transplantation
Conference Coverage
Murine studies support use of TKIs in ALL subtype
PHILADELPHIA—Experiments in mice reinforce the idea that tyrosine kinase inhibitors (TKIs) can treat patients with Ph-like acute lymphoblastic...
Conference Coverage
Drugs demonstrate inconsistent synergy in CLL, MCL
PHILADELPHIA—The Bcl-2 inhibitor ABT-199 and the Bruton tyrosine kinase inhibitor ibrutinib can have a synergistic effect against mantle cell...
Original Report
Practice gaps and barriers to optimal care of hematologic malignancies in the United States
News
Exercise boosts anticancer effects of doxorubicin
Credit: Aaron Logan Exercising during doxorubicin treatment can amplify the drug’s cancer-fighting ability, according to preclinical research....
News
Idelalisib approved to treat CLL, FL in EU
The European Commission has granted marketing authorization for the PI3K delta inhibitor idelalisib (Zydelig) to treat chronic lymphocytic...
News
Disrupting equilibrium to fight AML
Credit: Lance Liotta Understanding the relationship between mutated and wild-type genes could lead to new therapies for acute myeloid leukemia (...
News
Predicting chemo drugs’ effects on male fertility
Credit: Rhoda Baer A mathematical formula may help physicians predict which cancer survivors are likely to have normal sperm production following...
News
Drug shows activity in models of pediatric ALL
Credit: Aaron Logan A compound that has demonstrated efficacy in older adults with acute myeloid leukemia (AML) may be a viable option for...
News
FDA approves new treatment for PI
Credit: Baxter The US Food and Drug Administration (FDA) has approved a subcutaneous immune globulin product for use in adults with primary...
News
Patients with Ph-like ALL may benefit from TKIs
Credit: St Jude Children’s Research Hospital New research indicates that Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL)...
News
Antifungal shows promise in hematologic conditions
WASHINGTON, DC—A new antifungal agent is as effective as an existing drug against invasive mold infection in patients with hematologic disorders,...