Leukemia, Myelodysplasia, Transplantation
Conference Coverage
Jury still out on combo for elderly AML
Photo courtesy of NIH VIENNA—A 2-drug combination can produce complete responses (CRs) in elderly patients with newly diagnosed acute myeloid...
Conference Coverage
VIDEO: Ibrutinib should be therapy ‘backbone’ in relapsed CLL
Conference Coverage
Combo delays progression in relapsed CLL
VIENNA—Results of the COMPLEMENT 2 trial indicate that adding ofatumumab to treatment with fludarabine and cyclophosphamide (OFC) can improve some...
Conference Coverage
Dose reductions make ponatinib safer for CP-CML
VIENNA—Administering ponatinib at lower doses can reduce the risk of arterial occlusive events (AOE) without hindering responses in patients with...
Conference Coverage
Drug may be ‘important treatment option’ for AML
Photo courtesy of ASH VIENNA—Adding the anticancer quinolone derivative vosaroxin to treatment with cytarabine can improve outcomes for some...
News
Avocado-derived compound could treat AML
lab, surrounded by avocados Photo by Light Imaging/ University of Waterloo A compound derived from avocados could be effective in treating acute...
News
IDH1 inhibitor gets orphan designation for AML
The US Food and Drug Administration (FDA) has granted orphan designation for AG-120 to treat patients with acute myeloid leukemia (AML) who harbor...
News
Harnessing immune defense to treat Candida infection
An upset in the body’s natural balance of gut bacteria that may lead to life-threatening bloodstream infections can be reversed by enhancing an...
News
Pathway may play key role in FLT3-ITD AML
Results of preclinical research suggest the Hedgehog signaling pathway works with FLT3-ITD mutations to accelerate the development of acute...
Conference Coverage
A better FLT3 inhibitor for AML?
© ASCO/Scott Morgan CHICAGO—A dual inhibitor of FLT3 and Axl may produce more durable responses than other FLT3 inhibitors and improve survival...
News
Study reveals potential target for T-ALL
Photo by Rhoda Baer Targeting CXCL12/CXCR4 signaling could be a “powerful” approach to treating T-cell acute lymphoblastic leukemia (T-ALL),...