Leukemia, Myelodysplasia, Transplantation
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Retinoids, FAK inhibitors may aid TKIs in treating ALL subtype
and Charles Mullighan Photo courtesy of St.
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Inhibitors can target CML stem cells
Preclinical research has revealed nutrients that support the activity of chronic myelogenous leukemia (CML) stem cells and suggests these...
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Discovery reveals potential for viral cancer treatment
Image by Eric Smith Researchers say they have discovered critical details that explain how a cellular response system tells the difference...
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Team quantifies CAM use among seniors with cancer
Photo by Rhoda Baer A new study suggests that seniors with cancer may be taking complementary or alternative medicines (CAMs) without their...
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Persistent mutations tied to relapse, death in AML
Mutations that persist after initial chemotherapy may confer an increased risk of relapse and poor survival in patients with acute myeloid...
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Persistent mutations linked to poorer outcomes in AML
Key clinical point: Leukemia-associated mutations that persisted 30 days after chemotherapy initiation were associated with a significantly...
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BET inhibitor appears to cause memory loss in mice
Photo by Aaron Logan New research suggests the BET inhibitor JQ1 causes molecular changes in mouse neurons and can lead to memory loss in mice....
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Outcomes worse with secondary and therapy-related AML compared with de novo AML
Key clinical point: Younger patients with secondary and therapy-related acute myeloid leukemia (sAML and tAML, respectively) have worse outcomes...
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Pathway appears key to fighting adenovirus
Using an animal model they developed, researchers have identified a pathway that inhibits replication of the adenovirus. The team generated a new...
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T-cell finding may have broad implications
resolution microscope Image courtesy of UNSW Early exposure to inflammatory cytokines can “paralyze” CD4 T cells, according to research published...
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Team may have found earliest case of leukemia
archaeological dig (male, Late Bronze Age) Photo by Wessex Archaeology ZURICH—Researchers may have discovered the earliest known case of leukemia...