Leukemia, Myelodysplasia, Transplantation
Conference Coverage
Chemo quadruples risk for myeloid cancers
Key clinical point: This study quantifies the risks for treatment-related myeloid cancers after chemotherapy. Major finding: Chemotherapy is...
Conference Coverage
More complete cytogenetic responses at 12 months with radotinib than imatinib
Key clinical point: Radotinib was associated with significantly higher complete cytogenetic responses and major molecular responses than was...
Conference Coverage
Nilotinib safe, effective as first-line therapy for CML-CP patients age 65 and older
Key clinical point: Age did not affect molecular response or the incidence of adverse reactions to nilotinib among patients with CML-CP. Major...
News
A potential target for IDH1-mutant cancers
acute myeloid leukemia Researchers say they have identified a potential therapeutic target for IDH1-mutant malignancies. Preclinical experiments...
Conference Coverage
Osteoarticular pain affects CML patients stopping TKI
Photo courtesy of ASH ORLANDO, FL—Cases of musculoskeletal pain have been reported after patients stop taking tyrosine kinase inhibitors (TKIs)...
Conference Coverage
Anti-BCL2, CD20 combo safe, effective in untreated CLL
Key clinical point: Patients with CLL and comorbidities were able to tolerate an experimental regimen of obinutuzumab and venetoclax. Major...
Conference Coverage
CAR T cells persist for 3 years in young ALL patients
Photo courtesy of Penn Medicine ORLANDO, FL—CTL019, a CD19 chimeric antigen receptor (CAR) T-cell therapy, can persist for 3 years or longer in...
Conference Coverage
Venetoclax produces deep responses in ultra-high-risk CLL
Photo courtesy of ASH ORLANDO, FL—The pivotal phase 2 study of venetoclax monotherapy in patients with relapsed/refractory 17p-deleted chronic...
Conference Coverage
Regimen with intensified PEG-ASP feasible in young adults with ALL
Annual Meeting Photo courtesy of ASH ORLANDO, FL—Results of a DFCI ALL Consortium trial have shown that adults with acute lymphoblastic leukemia...
Conference Coverage
Academic hospitals offer better AML survival
Key clinical point: Academic hospitals tend to have better short- and long-term mortality for patients with AML than nonacademic hospitals. Major...
News
Group finds inconsistencies in genome sequencing procedures
Photo courtesy of NIGMS Researchers say they have identified substantial differences in the procedures and quality of cancer genome sequencing...