Gastrointestinal Cancer
News
Early mortality predicted by age and poor performance status in patients with colon cancer
Key clinical point: Among patients with colon cancer enrolled in phase III trials for adjuvant therapy, mortality within 6 months of random...
News
MAVERICC: Search for predictive biomarkers in first-line colorectal cancer trial goes on
Key clinical point: Tumor ERCC1 expression does not appear helpful for selecting a first-line regimen for colorectal cancer. Major finding: Among...
News
Office visits still common before colonoscopy
Nearly 30% of outpatient colonoscopies for colon cancer screening or polyp surveillance were preceded by a gastroenterology office visit, with...
News
RT for rectal cancer may reduce risk of some other cancers
Key clinical point: Patients with rectal cancer who receive radiation therapy have a lower risk of second pelvic tumors. Major finding: Compared...
Conference Coverage
Survival of pancreatic cancer is better when adjuvant therapy is given in high-volume centers
Receiving adjuvant therapy for pancreatic cancer at a center that treats a high volume of patients with the disease confers a survival advantage,...
News
PD-1 blockade impresses in mismatch repair–deficient GI cancers
Blockade of the cell surface receptor programmed death–1 (PD-1) is highly efficacious in patients with advanced noncolorectal cancers of the...
News
Immune checkpoint inhibitors have antitumor activity in gastric, esophageal cancers
Key clinical point: Nivolumab and pembrolizumab appear active and well tolerated in patients with previously treated esophagogastric cancers....
News
High participation, steady sensitivity for CRC with annual FIT screening
Annual fecal immunochemical testing (FIT) for colorectal cancer screening demonstrated slightly decreased but steady sensitivity and predictive...
News
Adjuvant oxaliplatin reduces colon cancer recurrence, deaths
Key clinical point: Adding oxaliplatin to fluoropyrimidine-based adjuvant chemotherapy significantly reduces the risk of recurrence of colon...
News
New neoadjuvant regimen for locally advanced rectal cancer is efficacious
Key clinical point: A regimen of short-course radiation followed by chemotherapy offers a new treatment option for patients with locally advanced...
News
Biomarker may ID high-risk colon cancers
A biomarker for which a screening test is already available – lack of CDX2 expression – appears to identify the approximately 20% of stage II and...