Conference Coverage
Conference Coverage
Adjuvant T-DM1 halves HER2-positive invasive breast cancer recurrence
SAN ANTONIO – The 3-year invasive disease-free recurrence was 88.3% for patients with residual disease treated with T-DM1 versus 77.0% with...
Conference Coverage
LCAR-B38M CAR T therapy appears durable in myeloma
SAN DIEGO – Positive phase 1 results keep LCAR-B38M in the CAR T race in multiple myeloma.
Conference Coverage
PD-L1 expression best predicts response to atezolizumab + nab-paclitaxel for mTNBC
SAN ANTONIO – IMpassion130 analyses show that PD-L1 expression on tumor-infiltrating immune cells is the best...
Conference Coverage
No boost in OS with addition of capecitabine for early TNBC
SAN ANTONIO – Adding adjuvant capecitabine to surgery and standard chemotherapy did not improve disease-free or overall survival in women with...
Conference Coverage
2018: A banner year for hematology drug approvals
SAN DIEGO – There have been 32 new hematology drug approvals and the year isn’t over yet.
Conference Coverage
Phase 3 study confirms biosimilarity of PF-05280586 with rituximab
PF-05280586 showed biosimilarity to rituximab at up to 26 weeks in a randomized phase 3 study of treatment-naive patients with CD20-positive LTB-...
Conference Coverage
Factor IX expression stable at up to 8 years with gene therapy
SAN DIEGO – In severe hemophilia B, factor IX expression remains stable up to 8.6 years after scAAV2/8-LP1-hFIX–comediated gene therapy.
Conference Coverage
Similarity of CT-P6 and trastuzumab remain with longer follow-up
The efficacy and cardiac toxicity profile between trastuzumab biosimilar candidate CT-P6 and trastuzumab, as neoadjuvant and then adjuvant therapy...
News
CLL resistance mechanism to venetoclax identified
SAN DIEGO – The mutation was present only after therapy in paired samples from patients enrolled in clinical trials of venetoclax.
Conference Coverage
KATHERINE: T-DM1 doubles HER2-positive invasive disease-free survival
SAN ANTONIO – For the primary endpoint of invasive disease-free survival, T-DM1 was associated with a hazard ratio of 0.50.
Conference Coverage
Large cohort study IDs prognostic factors in thromboangiitis obliterans
CHICAGO – Ethnicity and limb infection are independent predictors of poor outcomes, including limb amputation, in TAO.