Hospital mortality after allogeneic hematopoietic stem cell transplant (aHSCT) decreased, but long-term survival remained unchanged in a retrospective analysis involving 1,235 individuals.

Investigators looked a short- and long-term outcomes in patients admitted to the ICU over 12 years ending in 2013. Among the results:

• 161 patients were admitted to the ICU.

• Survival rates were as follows: ICU 65%; in-hospital 46%; 1-year 33%, 5-year 20%.

• Those who needed mechanical ventilation or vasopressor experienced worse overall survival.

• The need for mechanical ventilation and vasopressors decreased after 2008.

• Sepsis diagnosis also decreased after that time.

• Hospital mortality decreased to 44% from 69% over the course of the study; long-term survival stayed the same.

• Late deaths not linked with being in the ICU increased.

Citation: Mayer S, Pastores S, Riedel E, Maloy M, Jakubowski A. Short- and long-term outcomes of adult allogeneic hematopoietic stem cell transplant patients admitted to the intensive care unit in the peritransplant period. [Published online ahead of print June 27, 2016]. Leuk Lymphoma. doi:10.1080/10428194.2016.1195499.