Breast Cancer
News
Lymph node status predicted 10-year mortality in BRCA1 mutation carriers with small, stage I-III breast cancers
Major finding: Based on BRCA1 status alone, the 10-year survival rate for mutation carriers was 80.9% (95% CI, 75.4%-86.4%); for noncarriers, it...
News
Bernard Fisher at 95
News
Long-term CCB therapy linked to higher breast cancer risk
Major finding: Long-term use of calcium-channel blockers (10 years or more) was related to increased risk of breast cancer, with an OR of 2.4 for...
News
Age does not impact survival in HER2-positive breast cancer
Major finding: Among women with HER2 positive breast cancer, disease free survival (HR 1.18; 95% CI, 0.90-1.54) and overall survival (HR 1.01; 95...
Guidelines
Guidelines issued on radiation-induced heart disease
News
Stem cell mutations in breast cancer may confer metastatic risk
Major finding: Nine of 10 specimens with mutations in breast cancer stem and progenitor cells, as compared with 4 of 20 tumors without BCSC...
News
Racial discrepancy in breast cancer survival examined
Major finding: When breast cancer patients were matched for demographic characteristics at presentation, 5-year survival was 68.8% for white women...
News
Genetic alterations affect everolimus benefit in breast cancer
Major Finding: Everolimus decreased the risk of progression or death by 73% in patients whose tumors had none or one genetic alteration in the...
News
Upamostat falls short in HER2-negative metastatic breast cancer
Major finding: Adding upamostat vs. placebo did not significantly prolong progression-free survival in the entire trial population (8.3 vs. 7.5...
News
BOLERO 3: Everolimus may overcome trastuzumab resistance in HER2-positive breast cancer
Major finding: Compared with placebo, everolimus led to better progression-free survival when added to trastuzumab and vinorelbine (hazard ratio,...