Breast Cancer
News
Obesity increased breast cancer mortality only in premenopausal women
Major finding: Obesity was associated with a relative risk for death of 1.34 (95% confidence interval, 1.22-1.47) in premenopausal women; a weak,...
News
ASCO guidelines address targeted treatments of HER2-positive breast cancer
News
First SEER analysis including HER2 subtype is reported
Major finding: A total of 72.7% of invasive breast cancers diagnosed in the United States in 2010 were HR-positive (expressing either estrogen...
News
Trastuzumab emtansine linked to portal HT
Major finding: Two women who had normal results on liver CT before beginning trastuzumab emtansine therapy developed regenerative hyperplasia of...
News
Lower-dose chest radiation in childhood still carries high risk for breast cancer
Major finding: Whole-lung irradiation in childhood was associated with a high risk of subsequent breast cancer, compared with that in the general...
Conference Coverage
Topical lidocaine reduces menopausal dyspareunia
Key clinical point: Consider lidocaine as an option for women with severe menopausal dyspareunia for whom estrogen therapy is not recommended....
News
Pan-HER inhibitor ‘graduates’ from I-SPY 2 trial
Major finding: Among patients with HR-negative, HER2-positive breast cancer, the estimated pathological complete response was 56% for the...
News
Palbociclib shows promise in advanced ER-positive breast cancer patients
Major Finding: Median progression-free survival was 10.2 months among patients who received letrozole alone, compared with 20.2 months in patients...
News
First ASCO survivor care guidelines tackle fatigue, anxiety/depression, neuropathy
Community Translations
Pertuzumab in neoadjuvant treatment of HER2-positive early breast cancer
Pertuzumab injection was granted accelerated approval by the US Food and Drug Administration last fall for use in combination with trastuzumab...
News
Postmastectomy radiotherapy improves survival with one to three positive nodes
Major finding: Among those with one to three positive nodes, radiotherapy significantly reduced locoregional recurrence (RR, 0.68) and breast...