Editor-in-Chief Dr. David Henry highlights articles on T-DM1 for advanced HER2-positive breast cancer and an original research report from US Oncology on treatment patterns in women with HER2-/HR-positive breast cancer. He also looks at two case letters, one on plasmablastic lymphoma in the ileum, and a second on methotrexate-induced erythema multiforme, as well as a column by an oncology fellow on being a first-year fellow and first-year mom.