Plasmablastic lymphoma (PBL) is classified by the World Health Organization as a distinct type of diffuse large B-cell non-Hodgkin lymphoma, which is characterized by plasma cell differentiation and immunoblastic cell morphology.1 PBL usually develops in middle-aged adults, with the age at onset in one large series ranging from 35 to 55 years with male predominance.2-4 Although PBL has a strong affinity for the oral cavity, especially in HIV-positive patients, extraoral sites have also been reported.5-10 In this report, we describe an unusual case of PBL presented as multiple masses mostly located at the ileum, which resulted in small bowel obstruction.
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