"What this showed us is that it’s not just receiving a double perhaps that has some benefit for some patients, but also the conditioning regimen that we had changed simultaneously at the University of Minnesota," Dr. Wagner said.
He also highlighted similar findings from a very recent study he coauthored that reported comparable adjusted risks of neutrophil recovery, transplant-related mortality, and overall mortality after double UCB and adequately dosed single UCB transplants in 409 adults with acute leukemia (Blood 2012 Dec. 9 [Epub ahead of print]).
The study was supported by the National Heart, Lung, and Blood Institute; the National Cancer Institute; and the Children’s Oncology Group. Dr. Wagner and his coauthors reported no relevant conflicts of interest.