Reviews

Optimal integration of EGFR inhibitors in advanced colorectal cancer


 

42. De Roock W, Claes B, Bernasconi D, et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol 2010;11:753–762.
43. Laurent-Puig P, Cayre A, Manceau G, et al. Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer. J Clin Oncol 2009;27:5924–5930.

ABOUT THE AUTHORS
Affiliations: Drs. Nelson and Jasani are Assistant Professors, Department of General Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Conflicts of interest: The authors have nothing to disclose.

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