Anemia
News
More than 75% with sickle cell crises don’t get hydroxyurea
Key clinical point: More than 75% of adults with sickle cell anemia who have frequent pain crises fail to get hydroxyurea therapy as recommended....
News
Gene therapy appears effective against WAS
Photo by Chad McNeeley Results of a small study suggest gene therapy can lead to clinical improvements in children and teens with Wiskott-Aldrich...
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FDA grants drug orphan designation for SCD
Image by Graham Beards The US Food and Drug Administration (FDA) has granted orphan drug designation for the bovine PEGylated carboxyhemoglobin...
News
FDA approves new formulation of iron overload drug
Jadenu is now approved to treat patients 2 years of age and older who have chronic iron overload resulting from blood transfusions.
News
FDA strengthens warnings for anemia drug
Photo by Bill Branson The US Food and Drug Administration (FDA) has strengthened an existing warning that serious, potentially fatal, allergic...
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FDA grants drug orphan status to treat PKD
Image courtesy of NHLBI The US Food and Drug Administration (FDA) has granted orphan drug designation to AG-348 for the treatment of pyruvate...
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Prevalence of SDB in SCD may be high
Image by Graham Beards Results of a small study suggest there may be a high prevalence of sleep disordered breathing (SDB) in adults with sickle...
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Germline mutations linked to ALL
Photo by Rhoda Baer New research suggests that heritable mutations in the gene ETV6 can predispose people to acute lymphoblastic leukemia (ALL...
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Understanding the role of del(7q) in MDS
Image by James Thomson A new study has improved researchers’ understanding of a genetic defect associated with myelodysplastic syndromes (MDS),...
News
Enzyme keeps HSCs functional to prevent anemia
Preclinical research suggests an enzyme found in hematopoietic stem cells (HSCs) is key to maintaining periods of inactivity, thereby decreasing...
News
Team advocates liver MRI to measure iron
Magnetic resonance imaging (MRI) should be the gold standard for measuring liver iron concentration (LIC) in patients receiving ongoing...