AML
News
Drug receives fast track designation for FLT3+ rel/ref AML
The US Food and Drug Administration (FDA) has granted fast track designation to crenolanib for the treatment of patients with FLT3 mutation-...
From the Journals
Levofloxacin prophylaxis in AML reduces febrile neutropenia admissions
The results support recommendations made by the Infectious Diseases Society of America and the National Comprehensive Cancer Network.
News
Study reveals potential target for AML treatment
New research has revealed a potential therapeutic target for acute myeloid leukemia (AML)—the methyl transferase enzyme METTL3. Researchers found...
News
FDA grants drug orphan designation for AML, MDS
The US Food and Drug Administration (FDA) has granted orphan drug designation to AMV564, a CD33/CD3 bispecific antibody, for the treatment of...
From the Journals
Researchers identify potential gene target for AML drug development
Study pinpoints a new mechanism of gene regulation in acute myeloid leukemia.
News
Study reveals predictor of early mortality in AML
New research has shown an increased risk of early death in patients with acute myeloid leukemia (AML) who have high levels of indoleamine 2,3...
News
Method identifies effective treatments for leukemias, lymphomas
An ex vivo drug screening method can reveal optimal therapies for patients with hematologic malignancies, according to research published in The...
From the Journals
Novel agent to be studied in relapsed/refractory AML
The phase 1b/2 trial will study a polo-like kinase 1 inhibitor.
From the Journals
Start with fitness when deciding on treatment for elderly AML patients
In this difficult-to-treat population, fitness assessments help.
News
Team discovers mechanism of resistance in AML
Researchers say they have uncovered a target to overcome drug resistance in acute myeloid leukemia (AML). The team discovered how a linkage...
News
Rigosertib produces better OS in MDS than tAML
Rigosertib has demonstrated activity and tolerability in patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia transformed from...