Liver Disease
Conference Coverage
Fenofibrate fights increased triglycerides in NASH
BOSTON – Patients with advanced fibrosis caused by NASH had limited increase in triglycerides after treatment with varying doses of fenofibrate....
Conference Coverage
High doses of FXR agonist tropifexor reduce hepatic fat, serum ALT in patients with NASH
BOSTON – Mild pruritus, minor decreases in LDL cholesterol are notable adverse effects of treatment, similar to others in class.
Conference Coverage
Duodenal mucosal resurfacing has metabolic effects in type 2 diabetes
BOSTON – Improvements in HbA1c and NASH biomarker favored the procedure over sham procedure in first-ever randomized, double-blind...
From the AGA Journals
Blocking TLR9 may halt brain edema in acute liver failure
Experimental models have shown that ammonia exposure with astrocyte swelling and brain edema are potentiated by proinflammatory cytokines.
From the Journals
Liver abnormalities, disease common in patients with psoriatic arthritis
Patients for whom monitoring of liver function tests is recommended include those with high body mass index, daily alcohol intake, high damaged...
From the Journals
AGA Clinical Practice Update: Surveillance for hepatobiliary cancers in primary sclerosing cholangitis
Individuals with primary sclerosing cholangitis should be regularly checked for hepatobiliary cancers.
From the Journals
Fibrosis severity and cirrhosis drive patient-reported outcomes with NASH
NASH patients with advanced fibrosis have increased quality of life impairment when cirrhosis is included.
From the Journals
Direct-acting antiviral therapy boosts survival for infected HCC patients
Adults with a history of hepatocellular carcinoma had a significantly reduced risk of death after treatment of HCV infections with DAAs.
From the Journals
Increased levels of a bacterial strain may cause nonalcoholic fatty liver disease
Of the patients in the study with NAFLD, 61% carried high alcohol- and medium alcohol-producing Klebsiella pneumoniae, compared with 6.25...
From the Journals
Three factors predict 6-month mortality in patients with DILI
A web-based calculator is now available for clinicians to use in the clinic.