GI Oncology
From the AGA Journals
Loss of pancreatic E-cadherin contributes to carcinogenesis
In the presence of an oncogene, E-cadherin may play a pivotal role in pancreatic tumor formation.
Conference Coverage
Wide-area transepithelial sampling may be best method for detecting esophageal intestinal metaplasia
SAN ANTONIO – Forceps biopsy versus WATS in randomized clinical trial showdown.
Conference Coverage
Over half of NASH patients have improvement in liver fibrosis after bariatric surgery
BOSTON – Bariatric surgery brought significant weight loss and resolution of multiple metabolic comorbidities.
Conference Coverage
Direct-acting antiviral treatment linked to lower mortality in patients with HCC history
BOSTON – Reduced mortality in HCC patients with complete response apparently driven by achievement of sustained...
From the Journals
Postcolonoscopy colorectal cancers had unique features
Their predisposition to the proximal colon and to microsatellite instability suggests that they have unique characteristics of tumorigenesis.
From the Journals
Threshold for positivity affects FIT sensitivity for detecting CRC, advanced adenomas
Specificity varied together with positivity thresholds, but less substantially than sensitivity.
From the Journals
AGA Clinical Practice Update: Surveillance for hepatobiliary cancers in primary sclerosing cholangitis
Individuals with primary sclerosing cholangitis should be regularly checked for hepatobiliary cancers.
News
New practice guideline: CRC screening isn’t necessary for low-risk patients aged 50-75 years
For individuals aged 50-79 with no symptoms and an estimated 15-year CRC risk below 3%, no screening is recommended by BMJ Rapid Recommendations...
From the Journals
Two studies reveal preneoplastic links between H. pylori and gastric cancer
Perturbations to the CD44v9-xCT system often result in redox imbalance, and ultimately gastric metaplasia.
From the Journals
AGA Clinical Practice Update on the utility of endoscopic submucosal dissection in T1b esophageal cancer: Expert review
Endoscopic submucosal dissection (ESD) is a viable treatment option for patients with submucosal (T1b) esophageal cancer who have a low risk of...