GI Oncology
From the Journals
Endoscopic CRC resection carries recurrence, mortality risks
Success with this approach, however, depends upon accurate risk recurrence data, which have been lacking.
From the AGA Journals
Study reveals how aspirin may inhibit colorectal cancer
Aspirin rescued a proneoplastic intestinal phenotype, reduced stem cell expression and function, and increased the expression of an important Wnt...
From the Journals
CRC risk in young adults: Not as high as previously reported
Previous studies of colorectal cancer included carcinoid tumors as well as colorectal adenocarcinoma, which has inflated estimates of risk,...
From the Journals
Younger adults present with more advanced esophageal adenocarcinoma
The incidence of esophageal adenocarcinoma has risen threefold over the past 4 decades among patients younger than 50 years.
From the Journals
PDAC: Tumor reduction after neoadjuvant therapy may predict postsurgical survival
A 47% or more reduction in tumor size between endoscopic ultrasound and surgery predicted 3- and 5-year survival in pancreatic ductal...
From the Journals
Geography and behaviors linked to early-onset colorectal cancer survival in U.S. women
Physical inactivity and lower fertility correlate modestly with early-onset colorectal cancer mortality in women.
From the Journals
Pembrolizumab ‘preferred choice’ in MSI-H/dMMR metastatic CRC
Compared with chemotherapy, pembrolizumab doubled progression-free survival and improved the overall response rate in this patient population.
From the Journals
Hemochromatosis variants may confer 10-fold higher risk of liver cancer
Men of European ancestry had a greater risk of liver cancer and death if they had HFE variants.
Conference Coverage
Rapid relief of opioid-induced constipation with MNTX
Subcutaneously administered, peripherally acting mu-opioid receptor antagonist, relieves opioid-induced constipation in both chronic, noncancer-...
From the Journals
Task force recommends best practices for malignant colorectal polyps
Endoscopists should look for features of deep submucosal invasion and should retrieve, handle, and submit specimens in ways that support thorough...