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Dyspepsia Common in Gastroesophageal Reflux Patients

Clin Gastroenterol Hepatol; 2018 Jan; Eusebi, et al

Publish date:: January 15, 2018

The odds of patients with the symptoms of gastroesophageal reflux also having dyspepsia are quite high, according to a systematic review and meta-analysis that included >111,000 patients. Among the details:

The prevalence of dyspepsia among patients who reported weekly gastroesophageal reflux symptoms (GERS) was 43.9%.
The odds of a person with weekly symptoms of gastroesophageal reflux having dyspepsia were about 7 times greater than it occurring in a person without GERS.
The overlap between GERS and dyspepsia was >25%.
Researchers speculated that shared pathophysiological mechanisms may explain the overlap.

Citation:

Eusebi LH, Ratnakumaran R, Bazzoli F, Ford AC. Prevalence of dyspepsia in individuals with gastroesophageal reflux-type symptoms in the community: A systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2018;16:39-48.e1. doi:10.1016/j.cgh.2017.07.041.

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