DDSEP® 8 Quick Quiz

Quick Quiz Question 1

Publish date: July 30, 2021

Q1. A 42-year-old male on chronic opiates for history of old spinal injury was seen for dysphagia. The patient reports having dysphagia for solids and liquids for the last one year without anorexia or weight loss. Patient denies symptoms of heartburn or regurgitation. A recent upper endoscopy was unrevealing. A high-resolution esophageal manometry was ordered.

Which of the following manometric findings have been shown to be associated with chronic opiate use?

Type 1 achalasia

Ineffective esophageal motility

Esophagogastric junction outflow obstruction

Absent contractibility

Q1. Correct answer: C. Esophagogastric junction outflow obstruction.

Rationale
Recent studies recognized the role of medications in inducing esophageal motor disorders. Opiates have been shown to be associated with esophagogastric junction outflow obstruction, achalasia (not type 1), and other hypercontractile esophageal abnormalities.

Reference
Camilleri M et al. Clin Gastroenterol Hepatol. 2017 Sep;15(9):1338-49.

Next Article:

AGA News