Pharmacology
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Rosuvastatin again linked with risks to kidneys
Practice should more often heed FDA-recommended rosuvastatin dosages for patients with severe chronic kidney disease and step up monitoring for...
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Life-threatening adverse events in liver cancer less frequent with ICI therapy
While tyrosine kinase inhibitors were found to be associated with more serious adverse events, both treatments had similar toxic effects.
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Lung cancer treatment combo may be effective after ICI failure
Phase 2 trial offers hope of a chemotherapy-free option for patients with advanced NSCLC.
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Hormone therapy didn’t increase recurrence or mortality in women treated for breast cancer
Recurrence was increased with vaginal hormone therapy among those taking aromatase inhibitors.
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Statins linked to lower diabetes risk after acute pancreatitis
Similar benefits were seen with low, moderate, and high statin doses, as well as in cases of both mild and severe acute pancreatitis.
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Safest, most effective medications for spine-related pain in older adults?
Acetaminophen has a favorable safety profile for spine-related pain but nonsteroidal anti-inflammatory drugs (NSAIDs) have greater efficacy.
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No increase in overdose deaths with take-home methadone
The percentage of deaths involving methadone decreased from 4.5% in 2019 to 3.2% in 2021.
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Best meds for insomnia identified?
For many insomnia medications, there is a “striking” and “appalling” lack of long-term data.
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Risky business: Most cancer drugs don’t reach the market
The fact that 8% were withdrawn ... “elicits the question of how the approval process can be improved to avoid ineffective or harmful drugs from...
Conference Coverage
Pembrolizumab for melanoma bittersweet, doctor says
“Until we can further define who the highest-risk patients are, I think it’s hard to give it to everyone,” one doctor says.