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Practice Patterns in Management of Polycythemia Vera

J Natl Compr Canc Netw; 2016 Oct 14; Kander, et al

There is variability in diagnosis and treatment approaches of polycythemia vera (PV) even in light of WHO guidelines and the advances in JAK2 therapy, according to a survey of 71 hematologists.

Investigators surveyed clinicians about their diagnostic and treatment approaches of PV in the post-JAK2 V617F era. Among the results:

  • Diagnostic testing varied depending on clinical experience and practice type.
  • There were marked differences in target hematocrit and platelet count.

The authors concluded that US-based guidelines for myeloproliferative neoplasms are needed to create disease management consistency.

Citation:

Kander E, Moliterno A, Rademaker A, Streiff M, Spivak J, Stein B. Practice patterns in the diagnosis and treatment of polycythemia vera in the post-JAK2 V617F discovery era. J Natl Compr Canc Netw. 2016;14(10):1238-1245.