Mental Health
Q&A
Ginkgo is not a smart pill
Solomon PR, Adams F, Silver A, Zimmer J, DeVeaux R. Ginkgo for memory enhancement: a randomized controlled trial. JAMA 2002; 288:835–40.
Q&A
Risperidone improves behavior in children with autism
McCracken JT, McGough J, Shah B, et al, for Research Units on Pediatric Psychopharmacology Autism Network. Risperidone in children with autism and...
Clinical Inquiries
What are effective treatments for panic disorder?
EVIDENCE-BASED ANSWER: Selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), benzodiazepines (BDZs), and cognitive...
Applied Evidence
The Active Management of Depression
Primary care clinicians are ideally positioned to serve as the central health care providers for patients with major depression.
Q&A
Carbamazepine effective for alcohol withdrawal
Malcolm R, Myrick H, Roberts J, Wang W, Anton RF, Ballenger JC. The effects of carbamazepine and lorazepam on single versus multiple previous...
Clinical Inquiries
What are the treatment options for SSRI-related sexual dysfunction?
EVIDENCE-BASED ANSWER: Substituting bupropion, nefazodone, or mirtazapine is beneficial. (Grade of recommendation: B, randomized controlled trials...
Original Research
Association of higher costs with symptoms and diagnosis of depression
Q&A
Several depression screening tools work equally well
Williams JW, Noel PH, Cordes JA, Ramirez G, Pignone M. Is this patient clinically depressed? JAMA 2002; 287:1160–70.
Q&A
Switching antidepressant classes often works in treatment-resistant depression
Thase ME, Rush AJ, Howland RH, et al. Double-blind switch study of imipramine or sertraline treatment of antidepressant-resistant chronic...
Original Research
Factors associated with weaning in the first 3 months postpartum
Q&A
Are SSRIs and TCAs equally effective for the treatment of panic disorder?
Otto MW, Tuby KS, Gould RA, McLean RYS, Pollack MH. An effect-size analysis of the relative efficacy and tolerability of serotonin selective...