Clinical Inquiries
-
Clinical Inquiries
When should we treat isolated high triglycerides?
EVIDENCE-BASED ANSWER: No evidence exists that treating isolated high triglyceride levels in the absence of other risk factors prevents coronary...
-
Clinical Inquiries
Is combining ACE inhibitors and ARBs helpful or harmful?
EVIDENCE-BASED ANSWER: The combination of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) has been studied...
-
Clinical Inquiries
Does lowering diastolic BP to less than 90 mm Hg decrease cardiovascular risk?
EVIDENCE-BASED ANSWER: Although lowering diastolic blood pressure (DBP) is associated with reduced cardiovascular events, systolic blood pressure...
-
Clinical Inquiries
Should we screen adults for asymptomatic microhematuria?
EVIDENCE-BASED ANSWER: Screening patients for asymptomatic microhematuria does not appear to improve outcomes, since screening does not identify a...
-
Clinical Inquiries
What is the best treatment for Osgood-Schlatter disease?
EVIDENCE-BASED ANSWER: Osgood-Schlatter disease is a common cause of pain and tenderness at the tibial tuberosity in active adolescents. It is...
-
Clinical Inquiries
Which healthy adults should take aspirin?
EVIDENCE-BASED ANSWER: In adults with no history of cardiovascular disease, aspirin reduces the risk of nonfatal myocardial infarction (MI)....
Applied Evidence
-
Applied Evidence
Simplifying the language of evidence to improve patient care
Strength of Recommendation Taxonomy (SORT): A patient-centered approach to grading evidence in the medical literature
-
Applied Evidence
An ounce of prevention: The evidence supporting periconception health care
-
Applied Evidence
Relative risks and odds ratios: What’s the difference?
Commentary
-
Commentary
Making evidence user-friendly
-
Commentary
Nasal irrigation as adjunctive care for acute sinusitis
-
Commentary
CORRECTION
Practice Alert
Photo Rounds
-
Photo Rounds
Conjunctivitis and cervicitis
Q&A
-
Q&A
Treatment of high LDL saves lives of those with diabetes or cardiovascular disease
BACKGROUND: It is recommended that patients with diabetes mellitus but without symptomatic cardiovascular disease should receive lipid-lowering...
-
Q&A
Candesartan reduces cardiovascular death in CHF patients on ACE inhibitor
BACKGROUND: Despite high doses of an ACE inhibitor, some angiotensin II is still produced by the kidney. ARB treatment, in addition to an ACE...
-
Q&A
Vaccinations containing thimerosal do not increase rates of autism
BACKGROUND: Thimerosal has historically been used as a preservative in many vaccines. Thimerosal contains ethyl mercury that has been postulated...
-
Q&A
Antidepressant treatment reduces poststroke mortality
BACKGROUND: Depression commonly occurs after an acute stroke and is associated with an increased risk of poststroke mortality.
-
Q&A
Azithromycin (3 days) better than amoxicillin-clavulanate (10 days) for sinusitis?
BACKGROUND: Sinusitis is frequently treated with 7- to 14-day courses of antibiotics in primary care; however, several trials have shown success...
-
Q&A
Four-year prostate cancer screening interval is effective
BACKGROUND: Screening for prostate cancer is still controversial as it has not been shown to decrease mortality. A large randomized screening...
-
Q&A
Conjunctivitis: Diagnostic usefulness of signs and symptoms unknown
BACKGROUND: Primary care providers often prescribe antibiotics based on physical findings of papillary conjunctivitis, mucopurulent discharge, and...