Gastroenterology
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CT, CEA alone or combined better than nothing to detect colon cancer recurrence
Major finding: Colon cancer recurrences were detected (and operated upon) in 6.7% of the CEA-only group, 8% of the CT-only group, and 6.6% of the...
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Intussusception risk seen with newer rotavirus vaccines
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FLINT trial halted early because of positive results
Major finding: Treatment for nonalcoholic steatohepatitis with obeticholic acid resulted in a highly statistically significant improvement (P = ....
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Constipation drug overdose can cause heart, kidney problems
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Triple-antiviral therapy achieves 94% response without interferon, ribavirin
Major finding: By week 4, patients achieved a HCV-RNA level of less than 25 IU/mL; 97% maintained that level through the end of treatment.
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Skin patch vaccine for traveler’s diarrhea proves clinically unsuccessful
Major finding: The efficacy of skin patch vaccine containing ETEC heat-labile toxin was 34.6%, (95% CI –2.2 to 58.9; P = .0621), with no...
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Metronidazole linked to increased risk for inflammatory bowel disease
Major finding: Three studies provided data on use of metronidazole, which proved to have the highest associated risk for new cases of IBD with a...
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Low-FODMAP diet reduced IBS symptoms
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Despite benefits, ‘bundling’ endoscopy is not norm
Major finding: Of more than 12,000 Medicare patients who underwent upper and lower endoscopy, fewer than two-thirds had the procedures "bundled"...