Clinical Edge

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Nicotine replacement therapy beats varenicline for smokers with OUD

Key clinical point: Smoking cessation with nicotine replacement vs. varenicline results in less drug use among patients with opioid use disorder.

Major finding: Patients with opioid use disorder had 16.5 drug use days if they used varenicline, compared with 0.13 if they used nicotine replacement therapy at 4-6 months follow-up (P less than .026).

Study details: The findings are based on a randomized, controlled trial of 47 smokers with OUD and 90 smokers without OUD in a smoking cessation program.

Disclosures: The research was funded by the National Institute on Drug Abuse and the Department of Veterans Affairs. The authors reported no disclosures.

Citation:

REPORTING FROM CPDD 2019