The CIRRAL cohort is an ongoing study that will form the backbone for additional studies into HCC in alcoholic liver disease, Dr. Ganne observed. Biological samples are being stored and a prospective database has been set up to include details of all assessments performed. Three nested studies are underway: one is looking at genetics using biobanked material (PANGEN), another is using the database to understand the role of the intestinal microbiota (MACHA), and another is looking at the potential role of nutrition (ALICIR).
The French National Cancer Institute, the French Association for Cancer Research, and the French National Agency for Research on AIDS and Viral Hepatitis funded the study. Dr. Ganne has no conflicts of interest.