Conclusions
We hope that we have shown that carefully studying systematic reviews is both entertaining and instructive for clinical practice.* (Online tutorial) We have decided to stop treating patients with acute cough with their upper respiratory infections with b-agonists unless we hear wheezing or have a strong impression of previous asthma. Further research is unlikely to change this. We now regard the presence or absence of signs in people with injured knees with considerable skepticism and accept that there is even more uncertainty than we did before but await better quality research.