Practice Alert

US Preventive Services Task Force: The gold standard of evidence-based prevention

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The United States Preventive Services Task Force (USPSTF) was first formed in 1984 to assist physicians in making decisions about which preventive services to offer patients. It consists of a 15-member panel of independent scientists picked for their expertise in primary care, clinical prevention, and evidence-based methodology. The first set of recommendations was published in 1989 as the Guide to Clinical Preventive Services, and was revised in 1996 in the second edition. Recommendations are now published on the USPSTF web site (www.ahrq.gov/ clinic/uspstfix.htm).

The USPSTF uses an explicit set of steps and criteria to judge the effectiveness, harms, costs and benefits of preventive interventions: screening, counseling, and chemoprevention. Topics are suggested by outside partners, including the American Academy of Family Physicians, and are then sent to one of 13 evidence-based practice centers, where an extensive review is conducted of the current scientific literature on the topic. The evidence report is then reviewed by the 15-member USPSTF and a recommendation is made using the rating system described in TABLE 1. The current members of the USPSTF arefound at www.ahrq.gov/clinic/uspstfab.htm# Members. The staff for the task force is provided by the Agency for Health Care Quality and Research (AHRQ), one of the agencies in the Public Health Service of the US Department of Health and Human Services.

In addition to listing the recommendations and the rationales behind them, the USPSTF web site also provides the evidence report and a description of recommendations on that topic made by other organizations, with a discussion of clinical implications of the recommendation. During 2004, the USPSTF made or updated 29 recommendations ( TABLE 2 ). There were 5 A recommendations, 4 B recommendations, no C recommendations, 11 recommendations against an intervention (D recommendation), and 9 instances of insufficient evidence to make a recommendation.

TABLE 1
Standard recommendation language, USPSTF

RECOMMENDATION:
A Language: The USPSTF strongly recommends that clinicians routinely provide [the service] to eligible patients. (The USPSTF found good evidence that [the service] improves important health outcomes and concludes that benefits substantially outweigh harms.)
RECOMMENDATION:
B Language: The USPSTF recommends that clinicians routinely provide [the service] to eligible patients. (The USPSTF found at least fair evidence that [the service] improves important health outcomes and concludes that benefits outweigh harms.)
RECOMMENDATION:
C Language: The USPSTF makes no recommendation for or against routine provision of [the service]. (The USPSTF found at least fair evidence that [the service] can improve health outcomes but concludes that the balance of the benefits and harms is too close to justify a general recommendation.)
RECOMMENDATION:
D Language: The USPSTF recommends against routinely providing [the service] to asymptomatic patients. (The USPSTF found at least fair evidence that [the service] is ineffective or that harms outweigh benefits.)
RECOMMENDATION:
I Language: The USPSTF concludes that the evidence is insufficient to recommend for or against routinely providing [the service]. (Evidence that [the service] is effective is lacking, of poor quality, or conflicting and the balance of benefits and harms cannot be determined.)

TABLE 2
USPSTF recommendations made in 2004

A Recommendation (strongly recommends)
  • Screening all pregnant women for asymptomatic bacteriuria using urine culture at 12 to 16 weeks’ gestation.
  • Screening for hepatitis B virus (HBV) infection in pregnant women at their first prenatal visit.
  • Rh (D) blood typing and antibody testing for all pregnant women during their first visit for pregnancy-related care.
  • Screening for syphilis in persons at increased risk for syphilis infection.
  • Screen all pregnant women for syphilis infection.
B Recommendation (recommends)
  • Screening and behavioral counseling interventions to reduce alcohol misuse by adults, including pregnant women, in primary care settings.
  • Prescribing oral fluoride supplementation at currently recommended doses to preschool children older than 6 months of age whose primary water source is deficient in fluoride.
  • Repeated Rh (D) antibody testing for all unsensitized Rh (D)-negative women at 24 to 28 weeks’ gestation, unless the biological father is known to be Rh (D)-negative.
  • Screening to detect amblyopia, strabismus, and defects in visual acuity in children younger than age 5 years.
D Recommendation (recommends against)
  • Routine screening of men and nonpregnant women for asymptomatic bacteriuria.
  • Routine screening for bladder cancer in adults.
  • Routine screening with resting electrocardiography (ECG), exercise treadmill test (ETT), or electron-beam computerized tomography (EBCT) scanning for coronary calcium for either the presence of severe coronary artery stenosis (CAS) or the prediction of coronary heart disease (CHD) events in adults at low risk for CHD events.
  • Routine screening of the general asymptomatic population for chronic hepatitis B virus infection.
  • Routine screening for hepatitis C virus (HCV) infection in asymptomatic adults who are not at increased risk (general population) for infection.
  • Routine screening for HCV infection in adults at high risk for infection.
  • Routine screening of asymptomatic adolescents for idiopathic scoliosis.
  • Routine screening for ovarian cancer.
  • Routine screening for pancreatic cancer in asymptomatic adults using abdominal palpation, ultrasonography, or serologic markers.
  • Routine screening of asymptomatic persons who are not at increased risk for syphilis infection.
  • Routine screening for testicular cancer in asymptomatic adolescent and adult males.
I Recommendation (insufficient evidence)
  • Screening and behavioral counseling interventions to prevent or reduce alcohol misuse by adolescents in primary care settings.
  • Routine use of interventions to prevent low back pain in adults in primary care settings.
  • Routine screening with resting electrocardiography (ECG), exercise treadmill test (ETT), or electron-beam computerized tomography (EBCT) scanning for coronary calcium for either the presence of severe coronary artery stenosis or the prediction of coronary heart disease (CHD) events in adults at increased risk for CHD events.
  • Routine risk assessment of preschool children by primary care clinicians for the prevention of dental disease.
  • Routine screening of parents or guardians for the physical abuse or neglect of children, of women for intimate partner violence, or of older adults or their caregivers for elder abuse.
  • Screening asymptomatic persons for lung cancer with either low dose computerized tomography (LDCT), chest x-ray (CXR), sputum cytology, or a combination of these tests.
  • Routine screening of adults for oral cancer.
  • Routine screening by primary care clinicians to detect suicide risk in the general population.
  • Routine screening for thyroid disease in adults.

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