Dr. Henke said parinox may be safe for patients with a history of HIT unless they are at really high risk, but that filters are overused and controversial. He noted that the same hospital consortium is trying to validate the Caprini score among 10,000 patients, with 90-day data now available on 8,500 patients.
"The interesting thing about this study that struck me initially as different is that, regardless of the other preoperative risk factors, dual prophylaxis was independently protective regardless of risk factors," he added. "So even with a low-risk Caprini score, they should probably have dual prophylaxis just because the overall [VTE] rate is quite high compared to many other surgical procedures."
Dr. Henke, Dr. Galandiuk and Dr. Mansour reported no relevant conflicts of interest.