Major Finding: After 12 weeks of twice-weekly, 60-minute classes, the tai chi group had a significantly greater decrease in the total Fibromyalgia Impact Questionnaire (−27.8 points, 95% confidence interval −33.8 to −21.8) compared with controls who underwent education about pain management, plus stretching (−9.4 points, 95% CI, −15.5 to −3.4), P less than .001.
Data Source: A single-blind, randomized trial of tai chi compared with wellness education and stretching in fibromyalgia management.
Disclosures: Dr. Wang reported having no financial conflicts of interest. A coauthor reported financial relationships with Pfizer, Lilly, and Forest; several authors reported having received grants from the National Institutes of Health and the National Center for Complementary and Alternative Medicine, which cosponsored the study with the American College of Rheumatology and the Boston Claude D. Pepper Older Americans Independence Center.
Twice-weekly tai chi exercises led to a statistically significant decrease in fibromyalgia symptoms, compared with wellness education and stretching.
The finding, published online in the New England Journal of Medicine, is consistent with other studies that have shown the benefits of tai chi for fibromyalgia as well as pain, depression, and overall quality of life (N. Engl. J. Med. 2010;363:743-54).
Dr. Chenchen Wang, who is with the division of rheumatology at Tufts Medical Center in Boston, and her colleagues looked at patients seen at Dr. Wang's facility between July 2007 and May 2009.
All patients were at least 21 years old and met American College of Rheumatology (ACR) 1990 diagnostic criteria for fibromyalgia, including “history of widespread musculoskeletal pain on the right and left sides of the body as well as above and below the waist, with a minimum duration of 3 months, and tenderness on pressure at 11 or more of 18 specific sites,” Dr. Wang and her associates said.
Patients were excluded from the study if they had any tai chi training or serious comorbidities such as rheumatoid arthritis or other conditions that might limit their mobility; if they were pregnant or planning on becoming pregnant; or if they scored less than 24 out of 30 points on the Mini Mental State Examination.
The primary end point was improvement on the Fibromyalgia Impact Questionnaire (FIQ), which scores symptoms on a scale of 1-100, with 100 being the worst.
Thirty patients completed a 12-week, twice-weekly, 60-minute tai chi program, plus a 24-week evaluation. Participants also were encouraged to practice at home for 20 minutes per day on their own, and “to maintain their tai chi practice, using an instructional DVD, up until the follow-up visit at 24 weeks,” the investigators wrote.
Meanwhile, 29 control patients completed a twice-weekly, 60-minute wellness education and stretching program, plus the 24-week follow-up.
The program included a didactic portion on pain management strategies and nutrition, plus a portion devoted to stretching. Patients also were encouraged to stretch at home each day for 20-minute periods.
Both groups were predominantly female (greater than 85%) and had mean ages of 50 years and 51 years for the tai chi group and the control group, respectively.
The mean baseline FIQ score in the tai chi group was 62.9, compared with 68.0 in the control group; the rate of attendance was 77% and 70% for the active treatment and control group, respectively.
According to Dr. Wang and her associates, after 12 weeks the patients in the tai chi group had a significantly greater decrease in their total FIQ score, to 35.1 (−27.8 points, 95% confidence interval −33.8 to −21.8) compared with controls, who fell to 58.6 (−9.4 points, 95% CI, −15.5 to −3.4), for a between-group difference of slightly more than 18 points (P less than .001).
The improvement in symptoms held up at the 24-week mark, with a change from baseline among the tai chi group of −28.6 points from baseline (95% CI, −34.8 to −22.4), compared with −10.2 among controls (95% CI, −16.4 to −4.0).
Similar to findings at the 12-week mark, that amounted to a between-group difference of more than 18 points, P less than .001.
Dr. Wang and her associates also looked at any improvement in sleep, as measured on the Pittsburgh Sleep Quality Index, graded on a scale from 0 to 21, with higher score indicating poorer sleep.
At 12 weeks, the tai chi patients had reduced their score by 3.6 points from baseline, compared with 0.7 points for the control group (P less than .001); at 24 weeks, the tai chi practitioners had dropped their score by 4.2 points, compared with 1.2 among controls (P less than .007).