Our patientwas started on oral prednisone 60 mg/d with plans for a prolonged taper over 6 months under the close supervision of Rheumatology. His weakness and polyuria began to improve within a month, and lupus-related symptoms resolved within 3 months. His cytopenia also significantly improved, with the exception of refractory thrombocytopenia.
THE TAKEAWAY
SLE is a common diagnosis with multiple presentations. Although lymphadenopathy is not part of the clinical criteria for the diagnosis of SLE, multiple case studies have highlighted its prevalence among affected patients.1,2,4,9-17 APS and antiphospholipid antibodies are also absent in the diagnostic criteria despite being highly associated with SLE. Thus, co-presentation (as well as age and sex) can be helpful with both disease stratification and risk assessment once a diagnosis is made.
CORRESPONDENCE Isabella Buzzo Bellon Brout, MD, 409 West Broadway, Boston, MA 02127; isabella.brout@bmc.org