Addiction Medicine
Clinical Inquiries
What is the most effective nicotine replacement therapy?
EVIDENCE-BASED ANSWER: No single nicotine replacement therapy is most effective for all smokers. All forms of nicotine replacement therapy (gum,...
Q&A
12-hour protocol safe for cocaine-associated chest pain
BACKGROUND: In the first hour after cocaine use, there is a 24-fold increase in the risk of sustaining MI. In 2000, over $83 million was spent on...
Q&A
Does acetaminophen affect liver function in alcoholic patients?
BACKGROUND: Traditionally, acetaminophen use in alcoholics has been discouraged due to uncontrolled retrospective data (mostly case reports) that...
Q&A
Carbamazepine effective for alcohol withdrawal
Malcolm R, Myrick H, Roberts J, Wang W, Anton RF, Ballenger JC. The effects of carbamazepine and lorazepam on single versus multiple previous...
Clinical Inquiries
How effective are pharmacologic agents for alcoholism?
EVIDENCE-BASED ANSWER: Naltrexone (ReVia) and nalmefene (Revex) are the most effective agents for treating alcoholism. Acamprosate is effective...
Q&A
Does long-term bupropion (Zyban) use prevent smoking relapse after initial success at quitting smoking?
Hays JT, Hurt RD, Rigotti NA, et al. Sustained release bupropion for pharmacologic relapse after smoking cessation. Ann Intern Med 2001; 135:423-...
Original Research
Direct Observation of Smoking Cessation Activities in Primary Care Practice
Q&A
Can 2 screening questions accurately detect alcohol and other drug abuse in the primary care setting?
Brown RL, Leonard T, Saunders LA, Papasouliotis O. A two-item conjoint screen for alcohol and other drug problems. J Am Board Fam Pract 2001; 14:...
Original Research
Use of Office-Based Smoking Cessation Activities in Family Practices
Original Research
Physicians’ Advice to Quit Smoking
The Glass Remains Half Empty
Original Research
Remission Of Alcohol Disorders In Primary Care Patients
Does Diagnosis Matter?