Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

BMI and Coronary Heart Disease

What role does gender play?

Publish date:: July 1, 2015

The risk of developing coronary heart disease is the same for men and women with increased body mass index (BMI) across diverse populations, according to a cohort study of 1,219,187 participants and 37,488 incident cases of coronary heart disease. Researchers found:

• Higher BMI was significantly associated with age-adjusted coronary heart disease.

• The age-adjusted hazard ratios (HRs) did not differ between the sexes.

• Similar results were found after multiple adjustments.

Citation: Mongraw-Chaffin ML, Peters SA, Huxley RR, Woodward M. The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1.2 million participants. The Lancet Diabetes & Endocrinology, 2015:3[6]:437–449. doi: 10.1016/S2213-8587(15)00086-8.

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