Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending January 17, 2016

New Treatment for Diabetic Foot Ulcers , Wound regeneration matrix superior vs usual care

Insulin Pump Now Indicated in Children, Allows continuous subcutaneous insulin infusion

Older Patients and Deintensification, Study evaluates if it happens often enough

Winter, Spring, Summer, or Fall? , How seasonality impacts bariatric surgery

Revised Diabetes Recommendations from ADA , New advice on obesity, technology, and CV risks

More must reads

Must reads for theWeek ending December 27, 2015

FDA Approves Basaglar Injection for Diabetes , Approval granted via abbreviated pathway

Testing and Treating Patients With Diabetes, Study finds that many clinicians are overdoing it

Lifestyle Intervention and Gestational Diabetes , Effect on weight and physical activity evaluated

Incident and Recurrent Fibroids in Women , Effect of high testosterone and E2 levels analyzed

Testosterone Therapy and Hypogonadism , Effect on insulin sensitivity, lean mass and fat

More must reads

Must reads for theWeek ending December 20, 2015

Stress, Depression in Individuals With Diabetes, Odds of stroke and CV-related death evaluated

Surgical Weight Loss Impact on Bone Mineral Density, Reductions seen even with vitamin D supplementation

Gene Classifier Testing and Thyroid Nodules , Test’s value in surgical decision-making process

Tooth Loss in Patients With Diabetes, Data collected over 40 years analyzed

Testosterone Therapy and Prostate Cancer , Does treatment lead to high=grade disease?

More must reads

Must reads for theWeek ending December 13, 2015

FDA Approves Kanuma for LAL-D , For use in infants, children, and adults

More Fractures Seen With Canagliflozin, But…, …results might be driven by patient profile

Canagliflozin’s Effect on A1C Levels , Use with other antihyperglycemics also evaluated

Vigorous Intense Physical Activity Effect on CRP, Compared with no or low activity

Adding Metformin to Insulin in Patients With T1D , Did it offer sustained glycemic control?

More must reads

Must reads for theWeek ending December 6, 2015

Lactation’s Role In Preventing Diabetes , Potential value after gestational diabetes delivery

Pregnancy in Young Patients With Diabetes, Effect of birth control counsel, outcomes studied

"Social Jet Lag's" Impact on Diabetes Risk , How misaligned sleep timing affects the healthy

Prenatal PFOA Exposure and Child Adiposity , BMI increase between ages 2 and 8 evaluated

Early Probiotic Exposure’s Impact on T1D , Reduced risk of islet autoimmunity seen

More must reads

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