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Levonorgestrel intrauterine system superior for controlling menorrhagia

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Approval of levonorgestrel-IUS should be broadened in U.S.

At present, the levonorgestrel-IUS is approved for the indication of heavy menstrual bleeding in the United States only among women who first choose to use it as a contraceptive method, said Dr. Eve Espey.

Dr. Eve Espey

"The data from the study by Gupta et al support broadening its approval to include menorrhagia more generally, whether or not contraception is needed," she said.

Dr. Espey is with the department of obstetrics and gynecology at the University of New Mexico, Albuquerque. She reported no financial conflicts of interest. These remarks were taken from her editorial accompanying Dr. Gupta’s report (N. Engl. J. Med. 2013 Jan. 10 [doi:10.1056/NEJMe1214191]).


 

FROM THE NEW ENGLAND JOURNAL OF MEDICINE

Given that menorrhagia often persists for years, longer follow-up of these study subjects is planned. Additional intention-to-treat analyses will be done at 5 and 10 years, Dr. Gupta and his associates said.

This study was supported by the National Institute of Health Research Health Technology Assessment Programme. Dr. Gupta reported ties to Hodder Arnold Publishing, Ethicon Gynecare, and Femcare-Nikomed.

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