Rare Diseases
Case Letter
Cutaneous Collagenous Vasculopathy
In cutaneous collagenous vasculopathy, skin biopsy may demonstrate eosinophilic hyaline thickening of superficial dermal blood vessels with mild...
Make the Diagnosis
A 60-year-old white woman presented with a 3-month history of a painful, nonhealing ulceration on her left lateral lower leg
Although the exact cause is unclear, systemic diseases, such as hypercoagulable states, may predispose vessels to develop occlusion.
Daily News Podcast
Aspirin and Omega-3 fatty acids fail
Flu activity is ‘high’ in nine states.
Case Reports
Ice Pack–Induced Perniosis: A Rare and Underrecognized Association
Perniosis, or chilblain, is characterized by skin lesions that occur as an abnormal reaction to exposure to cold and damp conditions. Ice pack–...
Conference Coverage
RELIEF: In Behçet’s, apremilast improves oral ulcers for up to 28 weeks
Apremilast was safe and effective for treating oral ulcers in patients with Behçet’s disease in a phase 3 study
Case Reports
Ichthyosiform Sarcoidosis and Systemic Involvement
Ichthyosiform sarcoidosis is a rare variant of cutaneous sarcoidosis that is frequently associated with further internal...
From the Journals
AEDs strongly linked to rare serious skin reactions
The highest-risk AEDs were zonisamide, rufinamide, clorazepate, lamotrigine, carbamazepine, and phenytoin.
Case Reports
Concomitant Fibrofolliculoma and Trichodiscoma on the Abdomen
Fibrofolliculoma and trichodiscoma are adnexal tumors that arise from or around hair follicles and are two of the many characteristic features of...
Video
Technology offers new tools, challenges for rare-disease patients
WASHINGTON –
Video
Education and support enhance care for rare-disease patients
WASHINGTON –
Conference Coverage
Serlopitant quells prurigo nodularis in phase 2 study
PARIS – Multiple phase 3 trials are underway for this promising agent.