Psoriasis
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AHRQ: Evidence Insufficient to Compare Psoriatic Arthritis Drugs
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Get Perspective on Serious Infections With Biologic Therapies
Major Finding: The serious infection risk for psoriasis patients was in the range of 1.0-1.5 cases per 100 patient-years of therapy.Data Source: A...
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Noncompliance With Topical Therapies Hampers Tx Effectiveness
Major Finding: Thirty-one percent of the 322 patients exhibited "primary nonadherence," meaning they never collected their medication.
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Almost Half of Psoriasis Patients Have Metabolic Syndrome
Major Finding: Of psoriasis patients, 40% have the metabolic syndrome, approximately double the rate found in adults who do not have psoriasis....
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TNF Inhibitor Users Report Less Sick Leave
Major Finding: TNF-inhibitor users reduced the average sick leave time from 9.8 days per month at the start of treatment to 6.5 days after 6...
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Briakinumab, Ustekinumab Trials Point to Future Psoriasis Treatment
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Interrupting Biologic Therapy for Psoriasis: What to Expect
Major Finding: Of the patients, 45% were still at PASI 75-100 at the start of retreatment, 31% had dropped below PASI 50, and 24% were in between....
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Severe Skin Lesions Complicate Anti-TNF Therapy for IBD
Major Finding: Overall, 34% of patients taking anti-TNF-alpha drugs for inflammatory bowel disease discontinued treatment because of severe...
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Briakinumab Boosts Quality of Life for Psoriasis Patients
Major Finding: Scores on the Dermatology Life Quality Index declined by a mean of 10.3points with briakinumab, 8.1 points with etanercept, and 3.0...
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Canakinumab Proves Safe, Effective for Long-Term CAPS Treatment
Major Finding: Of 38 canakinumab-naive patients, 68% achieved a complete response based on physician global assessment of disease activity and...
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Juvenile Localized Scleroderma: Fewer Flares With Methotrexate
Major Finding: At the end of the 12-month study, 17 of 24 patients randomized to receive placebo and prednisone experienced a relapse, compared...