Dermatopathology

Photo Challenge

Yellowish Papulonodular Periorbital Eruption

Author:

Brian Chia, MBBS, MRCP

Hong Liang Tey, MBBS, MRCP, Mrcps

A 66-year-old woman with a history of type 2 diabetes mellitus and mild dyslipidemia presented with persistent lesions over the eyelids and cheeks...

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Article

Glomus Tumor of Uncertain Malignant Potential on the Forehead

Author:

Antonio D’antonio, MD, PhD

Maria Addesso, MD

Alessia Caleo, MD

Malignant glomus tumors (GTs) are rare, and diagnosis requires consideration of specific histologic criteria.

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Case Letter

Adult-Type Langerhans Cell Histiocytosis: Minimal Treatment for Maximal Results

Author:

Vikas Patel, MD

John C. Hall, MD

Kenneth R. Watson, DO

Adult-type Langerhans cell histiocytosis (ALCH) is characterized as a group of disorders associated with abnormal spread and proliferation of...

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Dermpath Diagnosis

Pretibial Myxedema

Author:

Heather M. Holahan, BA

Ronda S. Farah, MD

Brian L. Swick, MD

Pretibial myxedema is a cutaneous mucinosis associated with thyroid dysfunction. The differential diagnosis includes nephrogenic systemic fibrosis...

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Article

Buschke-Ollendorff Syndrome: Sparing Unnecessary Investigations

Author:

Tiziana Surrenti, MD

Francesco Callea, MD

Laura Tanturri De Horatio, MD

Buschke-Ollendorff syndrome (BOS) is an autosomal-dominant disease characterized by the association of connective tissue nevi and osteopoikilosis...

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Article

Eleven Years of Itching: A Case Report of Crusted Scabies

Author:

Nurdan S. Kutlu, MD

Enver Turan, MD

Asli Erdemir, MD

Crusted scabies is a rare and highly contagious form of scabies that is characterized by uncontrolled proliferation of mites in the skin,...

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Photo Challenge

Nontender Nodules on the Lower Lip

Author:

Jeffrey R. Smith, MD, MPH

Megan N. Moody, MD, MPH

A 71-year-old woman presented with multiple 3×3-mm, firm, nontender nodules of 3 years’ duration on the mucosal surface of the lower lip that...

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Case Letter

Plaques: A Rare Presentation of Acrokeratoelastoidosis

Author:

Jun-Hua Liu, MMS

Di-Qing Luo, MMS

Liang-Cai Wu, MMS

Acrokeratoelastoidosis (AKE) is a rare disease first described in 1953.

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Dermpath Diagnosis

Hailey-Hailey Disease

Author:

Chika Ohata, MD, PhD

Hailey-Hailey disease typically presents as suprabasal blisters with a perivascular and interstitial lymphocytic infiltrate. The differential...

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Article

Multicentric Primary Extramammary Paget Disease: A Toker Cell Disorder?

Author:

Pantea Hashemi, MD

Grace F. Kao, MD

Thomas Konia, MD

Toker cells are epithelial clear cells found in the areolar and nipple areas of the breast, vulvar region, and other apocrine gland–bearing areas...

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Case Letter

Disseminated Waxy Papules: A Sign of Systemic Disease

Author:

Aikaterini Patsatsi, MD

Aikaterini Kyriakou, MD, MSc

Abir Nasr, MD

Ioannis Efstratiou, MD

Dimitrios Sotiriadis, MD

Generalized lichen myxedematosus is an instructive example of skin lesions being the presenting sign of a systemic disease. The course of the...

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