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More Than 50 Allergens Linked with Skin Cleansers

Dermatitis; ePub 2017 Dec 18; Warshaw, et al

Many allergens, especially preservatives and surfactants, were associated with skin cleansers (SCs), according to a recent study. Most cases involved the hands and were occupationally related. A retrospective cross-sectional analysis was performed using North American Contact Dermatitis Group data, 2000–2014. Researchers found:

  • Of 32,945 tested patients, 1,069 (3.24%) had either allergic patch test (APT) reaction or irritant contact dermatitis (ICD) associated with SCs.
  • Of these, 692 (64.7%) had APT reaction only, 350 (32.7%) had ICD only, and 27 (2.5%) had both.
  • Individuals with APT reaction and/or ICD were more likely to have occupationally related skin disease for APT reaction and 10.0 for ICD, respectively.
  • As compared with those without APT reaction to SC, individuals with APT reaction had significantly higher frequencies of hand and arm dermatitis.
  • ICD was strongly associated with hand dermatitis.
  • >50 allergens were associated with SCs.
Citation:

Warshaw EM, Goodier MC, DeKoven J, et al. Contact dermatitis associated with skin cleansers: Retrospective analysis of North American Contact Dermatitis Group Data 2000–2014. [Published online ahead of print December 18, 2017]. Dermatitis. doi:10.1097/DER.0000000000000330.