Key clinical point: Better understanding of bacterial colonization of wounds may lead to improved wound healing.

Major finding: Sodium salicylate could interfere with quorum sensing – how bacteria communicate; there is a dysbiosis seen in wounds of patient with dystrophic epidermolysis bullosa; and certain bacterial species are more commonly found in dystrophic epidermolysis bullosa wounds and might contribute to the development of squamous cell cancer.

Study details: An oral presentation on bacterial communication, an analysis of the skin microbiome of eight patients with recessive dystrophic epidermolysis bullosa, and a retrospective analysis of 739 wound cultures taken between 2001 and 2017 from 158 patients enrolled in the Epidermolysis Bullosa Clinical Characterization and Outcomes Database (EBCCOD).

Disclosures: The research on sodium salicylate was supported by Mölnlycke Health Care. The EBCCOD-based research was supported by the Pediatric Dermatology Research Alliance, EB Research Partnership, and the Epidermolysis Bullosa Medical Research Foundation.