Do you prescribe nonsteroidal agents for children younger than 2 years?
Almost two-thirds (64%) of dermatologists do prescribe nonsteroidal agents for children younger than 2 years.
If yes, which nonsteroidal agents do you prescribe for children?
Of those dermatologists who indicated that they do prescribe nonsteroidal agents for children younger than 2 years, almost half (45%) prescribe pimecrolimus, while 36% prescribe crisaborole or tacrolimus.
Expert Commentary
Provided by Shari R. Lipner, MD, PhD (New York, New York)
We have limited options for US Food and Drug Administration (FDA)–approved therapies for atopic dermatitis in children younger than 2 years. The risks of adverse effects also are higher in younger children compared to older children and adults, particularly hypothalamic-pituitary-adrenal suppression with corticosteroids. Pimecrolimus was the most common nonsteroidal prescribed in this group. It should be noted that pimecrolimus is not FDA approved for use in children younger than 2 years; however, 2 phase 3 studies were conducted with 436 infants aged 3 months to 23 months and they demonstrated safety and efficacy.
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