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Paraneoplastic syndrome and underlying breast cancer: a worsening rash despite initiation of chemotherapy
Skin may show the first clinical evidence of systemic disease and can be the first clue to malignancy in 1% of cases.1 Dermatomyositis is an immunologically mediated inflammatory myopathy characterized by proximal muscle weakness, muscle inflammation, and characteristic skin findings.2 It has an incidence of 1 in 100,000 patients.3 In 15%- 30% cases of dermatomyositis, an underlying malignancy is the cause of paraneoplastic syndrome.4,5 Ovarian and breast cancer in women and lung cancer in men are the most common malignancies associated with dermatomyositis.6
 
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The Journal of Community and Supportive Oncology - 14(5)
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229-231
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skin rash, paraneoplastic syndrome, dermatomyositis, breast cancer
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Article PDF
Skin may show the first clinical evidence of systemic disease and can be the first clue to malignancy in 1% of cases.1 Dermatomyositis is an immunologically mediated inflammatory myopathy characterized by proximal muscle weakness, muscle inflammation, and characteristic skin findings.2 It has an incidence of 1 in 100,000 patients.3 In 15%- 30% cases of dermatomyositis, an underlying malignancy is the cause of paraneoplastic syndrome.4,5 Ovarian and breast cancer in women and lung cancer in men are the most common malignancies associated with dermatomyositis.6
 
Click on the PDF icon at the top of this introduction to read the full article. 
 
Skin may show the first clinical evidence of systemic disease and can be the first clue to malignancy in 1% of cases.1 Dermatomyositis is an immunologically mediated inflammatory myopathy characterized by proximal muscle weakness, muscle inflammation, and characteristic skin findings.2 It has an incidence of 1 in 100,000 patients.3 In 15%- 30% cases of dermatomyositis, an underlying malignancy is the cause of paraneoplastic syndrome.4,5 Ovarian and breast cancer in women and lung cancer in men are the most common malignancies associated with dermatomyositis.6
 
Click on the PDF icon at the top of this introduction to read the full article. 
 
Issue
The Journal of Community and Supportive Oncology - 14(5)
Issue
The Journal of Community and Supportive Oncology - 14(5)
Page Number
229-231
Page Number
229-231
Publications
Publications
Topics
Article Type
Display Headline
Paraneoplastic syndrome and underlying breast cancer: a worsening rash despite initiation of chemotherapy
Display Headline
Paraneoplastic syndrome and underlying breast cancer: a worsening rash despite initiation of chemotherapy
Legacy Keywords
skin rash, paraneoplastic syndrome, dermatomyositis, breast cancer
Legacy Keywords
skin rash, paraneoplastic syndrome, dermatomyositis, breast cancer
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JCSO 2016;14(5):229-231
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