Applied Evidence
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Applied Evidence
Personalized medicine: The promise, the reality
Genetic testing can tell us how a patient will metabolize warfarin, but no one can tell us how to adjust our dosing.
Clinical Inquiries
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Clinical Inquiries
What is the recommended workup for a man with a first UTI?
EVIDENCE-BASED ANSWER: obtain a urine culture in all men with suspected urinary tract infection (UTI), to reliably diagnose an infection (strength...
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Clinical Inquiries
What is the best initial treatment for orbital cellulitis in children?
EVIDENCE-BASED ANSWER: Although antibiotics are the best initial treatment, surgical intervention is warranted when a child has the following.
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Clinical Inquiries
Is guaifenesin safe during pregnancy?
EVIDENCE-BASED ANSWER: It’s not clear; little evidence supports or refutes the safety of guaifenesin, a common expectorant, in pregnancy. A small...
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Clinical Inquiries
How should you treat Candida vaginitis in patients on antibiotics?
EVIDENCE-BASED ANSWER: Oral and intravaginal antifungals for the treatment of uncomplicated vulvovaginal candidiasis (VVC) have similar...
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Clinical Inquiries
Alcoholic liver disease: Is acetaminophen safe?
EVIDENCE-BASED ANSWER: Yes—acetaminophen is a safe and effective analgesic that can be appropriately used for adult patients with stable chronic...
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Clinical Inquiries
What’s the best treatment for CIN 2 or 3?
EVIDENCE-BASED ANSWER: Excision or ablation of the transformation zone are equally effective for treating an initial diagnosis of cervical...
Commentary
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Commentary
Up on the hill with the homeless
Original Research
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Original Research
A cheaper, faster way to resolve chronic cough
“Presumed diagnosis” strategy offers early treatment, a cost savings, and >90% treatment response.
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Original Research
Talking to patients about screening colonoscopy—where conversations fall short
This mixed-methods study reveals 6 key points often neglected in physician-patient discussions.
Photo Rounds
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Photo Rounds
A bright red pruritic rash on the forearms