Applied Evidence
Original Research
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Original Research
Second thoughts on integrative medicine
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Original Research
Are antibiotics beneficial for patients with sinusitis complaints?
A randomized double-blind clinical trial
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Original Research
Using the likelihood ratio
Practice Alert
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Practice Alert
Cause-of-death certification: Not as easy as it seems
Clinical Inquiries
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Clinical Inquiries
Do insulin-sensitizing drugs increase ovulation rates for women with PCOS?
EVIDENCE-BASED ANSWER: Short-term use of metformin (Glucophage) improves ovulation rates for women with polycystic ovary syndrome (PCOS) (strength...
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Clinical Inquiries
What are effective treatments for oppositional and defiant behaviors in preadolescents?
EVIDENCE-BASED ANSWER: Parent training is effective for treating oppositional and defiant behaviors (strength of recommendation [SOR]: A, based on...
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Clinical Inquiries
What is the most effective treatment for ADHD in children?
EVIDENCE-BASED ANSWER: Stimulant medication therapy is the most effective treatment for attention deficit/hyperactivity disorder (ADHD) in...
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Clinical Inquiries
What is the interval for monitoring warfarin therapy once therapeutic levels are achieved?
EVIDENCE-BASED ANSWER: The international normalized ratio (INR) should be measured monthly once therapeutic levels are achieved and are stable for...
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Clinical Inquiries
What are the causes of hypomagnesemia?
EVIDENCE-BASED ANSWER: The causes of magnesium depletion and hypomagnesemia are decreased gastrointestinal (GI) absorption and increased renal...
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Clinical Inquiries
What are effective therapies for Clostridium difficile-associated diarrhea?
EVIDENCE-BASED ANSWER: Oral metronidazole and oral vancomycin are equally effective treatments for Clostridium difficile–associated diarrhea (CDAD...
Commentary
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Commentary
Acute sinusitis, antibiotics, and the Holy Grail
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Commentary
I met a genie
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Commentary
Levothyroxine and FDA bioequivalence ratings
Photo Rounds
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Photo Rounds
Persistent itchy pink rings
Q&A
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Q&A
Useful treatments for fibromyalgia syndrome
CLINICAL QUESTION: What treatment modalities are most effective for fibromyalgia syndrome?STUDY DESIGN: Meta-analysis (other)SETTING: Various (...
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Q&A
Tight blood pressure control prevents blindness in patients with diabetes
CLINICAL QUESTION: Does tight blood pressure control improve visual outcomes in diabetic hypertensive patients?
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Q&A
ARB no better than ACE inhibitor for prevention of nephropathy progression
CLINICAL QUESTION: Are angiotensin receptor blockers as good as angiotensin-converting enzyme inhibitors at preventing the progression of...
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Q&A
Adding ACE inhibitor doesn’t improve outcomes in stable angina and normal LVEF
CLINICAL QUESTION: Does adding an angiotensin-converting enzyme inhibitor improve outcomes among patients with stable angina and no evidence of...
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Q&A
Cost-effective management for nephrolithiasis
CLINICAL QUESTION: What are the most cost-effective treatment strategies for the medical management of patients with kidney stones?