Applied Evidence
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Applied Evidence
Exercise and antidepressants improve fibromyalgia
Clinical Inquiries
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Clinical Inquiries
Should we discontinue Pap smear screening in women aged >65 years?
EVIDENCE-BASED ANSWER: Women with a history of regular, normal Pap smear screening should discontinue screening by age 65 years (strength of...
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Clinical Inquiries
Is the ThinPrep better than conventional Pap smear at detecting cervical cancer?
EVIDENCE-BASED ANSWER: Conclusions regarding the ThinPrep are difficult to make due to the complexity of cervical cancer screening and the lack of...
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Clinical Inquiries
Does treatment of acne with Retin A and tetracycline cause adverse effects?
EVIDENCE-BASED ANSWER: Adverse reactions to long-term tetracycline therapy are rare, and most will occur within 2 months of initiating therapy (...
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Clinical Inquiries
Is exercise treadmill testing useful for detecting heart disease in women?
EVIDENCE-BASED ANSWER: Exercise treadmill testing has a sensitivity of 70% and specificity of 61% for the detection of coronary artery disease (...
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Clinical Inquiries
How effective are leukotriene inhibitors for asthma in children?
EVIDENCE-BASED ANSWER: Evidence on the use of leukotriene inhibitors in children is insufficient to permit conclusions regarding efficacy. Given...
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Clinical Inquiries
Which blood tests are most helpful in evaluating pelvic inflammatory disease?
EVIDENCE-BASED ANSWER: No individual or combination of blood tests can reliably diagnose pelvic inflammatory disease (PID) (strength of...
Commentary
Case Reports
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Case Reports
Sudden loss of vision
Original Research
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Original Research
Self-doctoring: A qualitative study of physicians with cancer
Photo Rounds
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Photo Rounds
Painful and swollen hands
Practice Alert
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Practice Alert
Hepatitis A: Matching preventive resources to needs
Q&A
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Q&A
Metformin-induced lactic acidosis extremely rare
CLINICAL QUESTION: What is the risk of lactic acidosis accompanying metformin therapy for patients with type 2 diabetes? STUDY DESIGN: Systematic...
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Q&A
Ximelagatran effective in preventing stroke in a nonvalvular atrial fibrillation
CLINICAL QUESTION: Is ximelagatran as effective as warfarin in preventing stroke for patients with nonvalvular atrial fibrillation?
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Q&A
Hyaluronic acid minimally effective for knee osteoarthritis
CLINICAL QUESTION: Is intra-articular hyaluronic acid effective in the treatment of knee osteoarthritis?
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Q&A
Annual proteinuria screening not cost-effective
CLINICAL QUESTION: Is annual proteinuria screening in adults cost-effective? STUDY DESIGN: Cost-effectiveness analysis SETTING: Not applicable...
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Q&A
HPV testing may replace Pap smears for primary screening
CLINICAL QUESTION: Can human papillomavirus testing replace Papanicolaou tests as the primary means of screening for cervical cancer?